The CS3MESH4EOSC project was an official supporter of CS3 Conference 2022. The CS3 community consists of providers, developers, and users of innovative storage and sync&share systems. Its services are integrated with user environments and higher-level application services. Furthermore, CS3 reports on the progress in data science at all levels, namely local laboratories, regional collaborations, and global science. CS3 applications range from innovative big- data analysis to science outreach and education.